Multiple system atrophy (MSA) is a relentlessly progressive adult-onset synucleinopathy characterised by the intracytoplasmic accumulation of α-synuclein in oligodendrocytes, manifesting as glial ...

Dysregulation of the dopamine neurotransmitter system has long been associated with schizophrenia and other forms of psychosis, but recently researchers have begun to examine the glutamate and GABA ...

Muscle atrophy is a primary characteristic of both sarcopenia and cachexia, significantly impacting physical function and quality of life. This figure illustrates the multifaceted causes of muscle ...

With the intensification of global population aging, muscle atrophy, characterized by the loss of muscle mass and function, has become an important health issue affecting the elderly. Researchers have ...

Muscle atrophy models are crucial for understanding disease mechanisms and developing treatments. These models are used to study various interventions, such as exercise and nutrition, drug development ...

Before approval of the two intravitreal treatments for geographic atrophy (GA), the only evidence‑based intervention for slowing down progression of age-related macular degeneration (AMD) into more ...

Regardless of efforts taken to slow disease progression, in the absence of a curative option to either entirely halt progression or repair the damage to the retina, patients with geographic atrophy ...

While there is currently no cure for geographic atrophy, certain treatments, such as complement inhibitors, can help slow its progression by targeting immune system activity that damages the macula.

To continue reading this content, please enable JavaScript in your browser settings and refresh this page. Preview this article 1 min A University of North Florida ...