Dr. Timothy Palzkill, professor of Pharmacology and Chemical Biology ... to understand details about the structure and function of both groups of the beta-lactamases and their interactions with ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome ...

However, the nonribosomal peptide antibiotics are very complex structures which are difficult and expensive to produce by normal chemical methods. To address this, the Manchester team use gene editing ...