Ketamine is frequently used to induce analgesia or anesthesia in laboratory animals, but its effects on learning and memory are poorly characterized. Long-term potentiation (LTP) is considered a ...

Intravenous (i.v.) anesthetics include etomidate, midazolam, propofol, thiopental, ketamine, and opioid agonists. The first four agents act by enhancing the activity of the inhibitory neurotransmitter ...

Though it may be a surprise to the millions of people who undergo general anesthesia every year for medical procedures, the biological mechanism for how different anesthetics block consciousness is ...

The reliance on brain atlases for high-precision placement of injectable substances in the brain of NHPs has substantial disadvantages. To overcome the issue of inter-animal variability, we developed ...

Older patients who received anesthesia with etomidate had no higher risk of major complications after elective abdominal surgery compared to propofol, a randomized trial found. Among 1,917 such ...

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General anesthesia is medicine you get before surgeries that require you to be in a deep sleep-like state. It is given in stages – just before the surgery begins and then throughout the surgery to ...

Purpose: The characteristics of ideal intravenous (i.v.) and inhaled anesthetic agents; the rationale for inducing anesthesia with i.v. anesthetics (particularly propofol); therationale for inducing ...