Charlotte's 49ers ended a three-game losing streak, blowing past Tulane in the second half in the American Conference tournament Thursday.

Brandon Aiyuk scored the winning touchdown reception in overtime as the San Francisco 49ers rallied to beat the Cincinnati Bengals 26-23 in one of the most thrilling games of the season. Aiyuk ...

He stepped up when the 49ers needed him most.

The San Francisco 49ers and Seattle Seahawks face off for the third time this season. They split the two meetings in the regular season with the road team coming out on top, and now a trip to the NFC ...

"The whole time I'm in the game, I just felt really weird." ...

The San Francisco 49ers allowed three defensive tackles to become unrestricted free agents, and now two have left for other teams.

A trip to Mexico will mark the second of two international contests for the 49ers in 2026. They also face the Rams as the ...