Michael Martynowycz, PhD, assistant professor of structural biology at the Jacobs School of Medicine and Biomedical Sciences, recently described a new technique for solving protein structures in a rec ...

A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

This review provides an overview of traditional and modern methods for protein structure prediction and their characteristics and introduces the groundbreaking network features of the AlphaFold family ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and biomarker discovery in proteomics.

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...